Heart Disease Risk Factors: What You Can and Cannot Change
Heart disease risk comes from a mix of things you can change and things you cannot. This article lists the main risk factors and explains why knowing them matters.
Educational information only, not medical advice. Always ask a qualified doctor about your own health. In an emergency call 112 (India) or 911 (US). Read the full disclaimer.
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Anyone can develop heart disease, but some people are more likely to than others. Knowing your risk factors helps you and your doctor decide what to check and what to change. This article draws on the CDC, WHO and NHS. A risk factor raises the chance of a problem. It does not mean you will definitely get it.
The three key risk factors
The CDC says high blood pressure, high blood cholesterol and smoking are the key risk factors for heart disease, and that 47% of people in the United States have at least one of the three. High blood pressure and high cholesterol usually cause no symptoms, so they are often found only through checks.
Risk factors you can change
The CDC lists these controllable factors:
- High blood pressure, high cholesterol, diabetes and obesity
- Diets high in saturated fat, trans fat, cholesterol or salt
- Not getting enough physical activity
- Drinking too much alcohol
- Tobacco use, including exposure to second-hand smoke
The WHO groups behavioural risks as an unhealthy diet, physical inactivity, tobacco use and harmful use of alcohol. It also names air pollution as an environmental risk, and says high blood pressure, high blood glucose, high blood fats and overweight are intermediate risks. The CDC notes a link between heart disease and mental health conditions.
Risk factors you cannot change
The NHS lists several factors that can increase the chance of cardiovascular disease:
- Age: it mainly affects people over 50.
- Sex: men are more likely to develop it than women.
- Ethnicity: the likelihood is higher for people from South Asian, Black African or African Caribbean backgrounds.
- Family history: having a close relative with cardiovascular disease.
The CDC adds that genes likely play a role in high blood pressure and heart disease, and that family habits may also contribute. It says family history combined with unhealthy choices, such as smoking or a poor diet, can raise risk further. The WHO also lists poverty, stress and heredity among the wider determinants.
Why knowing your risk helps
Even if some factors cannot be changed, many others can. The CDC says the main message is to know your risk so you can prevent heart disease. The NHS says a health check for people aged 40 to 74 in the UK can show whether someone is at higher risk, and that statins may be advised for people at high risk. Ask your doctor what checks are available where you live.
Steps to take
No one can change their age or family history, but the list of things you can do is long. A good first step is simply to find out your numbers. Start with a few of these, and add more over time:
- Have your blood pressure, cholesterol and blood sugar checked
- Do not smoke, and avoid second-hand smoke
- Eat a balanced diet that is lower in salt and saturated fat
- Be active in ways your doctor says are safe for you
- Keep to a healthy weight
- Take prescribed medicines as directed
When to see a doctor
See a doctor if you have several risk factors, a close relative who had heart disease at a young age, or you have never had a heart check. Tell them about your family history and ethnicity, as these affect how your risk is assessed.
Call emergency services at once for chest pain that is tight or squeezing, pain spreading to the arms, neck or jaw, severe breathlessness, or sudden weakness or numbness on one side of the face or body. The NHS advises not to drive yourself to hospital.
In an emergency, call your local emergency number (112 in India, 911 in the United States).
Common questions
What are the main risk factors for heart disease?
The CDC names high blood pressure, high blood cholesterol and smoking as the key risk factors.
Which risk factors can I change?
The CDC lists high blood pressure, high cholesterol, diabetes, obesity, an unhealthy diet, inactivity, too much alcohol and tobacco use as controllable.
Does ethnicity affect risk?
The NHS says the likelihood of cardiovascular disease is higher for people from South Asian, Black African or African Caribbean backgrounds.
Does a family history mean I will get heart disease?
Not necessarily. The CDC says family history can raise risk, especially combined with unhealthy habits, but many other risk factors can be changed.
Important: please read
- Educational information only. This article is general health education. It is not medical advice, diagnosis or treatment. Reading it does not create a doctor–patient relationship with MyDoctor or with anyone else.
- Ask a qualified doctor. Always talk to a qualified, registered doctor about your own health. In India, that means a doctor registered with the National Medical Commission (NMC) or a State Medical Council. In the United States, a licensed physician. Elsewhere, a doctor licensed where you live.
- Never ignore or delay professional advice because of something you read here. Do not start, stop or change any medicine or treatment without your doctor.
- Emergencies: call 112 in India, 911 in the United States, or your local emergency number. Do not wait for an online answer.
- No product is endorsed. MyDoctor does not recommend any brand, product or supplement in this article.
- About the sources. This article summarises, in our own words, information from the public health bodies named under Sources. Health knowledge changes, and this summary may not reflect the latest research or your personal situation.
- Liability. To the extent permitted by law, MyDoctor (MODERNUS HEALTH TECHNOLOGIES PRIVATE LIMITED) accepts no liability for any decision made on the basis of this content.
Sources
- CDC. Heart Disease Risk Factors - CDC www.cdc.gov
- CDC. About Heart Disease - CDC www.cdc.gov
- NHS. Cardiovascular disease - NHS www.nhs.uk
- WHO. Cardiovascular diseases (CVDs) fact sheet - WHO www.who.int

Dr. Ambed Mishra, PharmD, PhD
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MyDoctor by MODERN US HEALTH, Austin, Texas. Ahmedabad, Gujarat. Bangalore, India.
Dr. Ambed Mishra is a clinical (patient care) scientist, author and former professor. He is Group CEO and Chief Medical Officer of MODERN US HEALTH (MODERN US GROUP), Austin, Texas, the group behind MyDoctor, and a senior consultant who teaches and trains MD/DO physicians, PharmD and PhD professionals, nurses and other healthcare professionals in patient care in the United States and India.
More about Dr. Ambed Mishra
- More than ten years of full-time leadership in United States healthcare, building patient care services that improve medication adherence and bring doctors, pharmacists and nurses together around each patient.
- Leads the MD and engineering teams behind MyDoctor: clinic and hospital management software, electronic health records and telehealth for hospitals and physician groups in the United States and India.
- Former Assistant Professor and Clinical Preceptor at Rajiv Gandhi University of Health Sciences, Bangalore, and senior researcher with hospitals, universities and patient care groups in India and the United States.
- More than 30 published research and review articles and case reports, and more than 15 international conference presentations in India, Australia, Canada, the United States, Spain and other countries.
- Chief Medical Officer and Global Program Head of a nonprofit mission that helps cover hospital and doctor visit bills for patients in need in India, Nepal, the United States and other countries.
The author's office answers questions about articles, research, speaking and collaboration. It cannot give personal medical advice.