Depression Symptoms: Signs to Notice and When to Get Help
Depression can show up in feelings, the body and behaviour, and sometimes others notice it first. This article lists common symptoms and explains when to seek help.
Educational information only, not medical advice. Always ask a qualified doctor about your own health. In an emergency call 112 (India) or 911 (US). For mental health support call Tele-MANAS 14416 (India) or 988 (US). Read the full disclaimer.
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Depression does not always look like sadness. It can show up in your thoughts, your body and your behaviour, and it often builds slowly. This article lists the symptoms described by the UK's National Health Service (NHS), MedlinePlus and the World Health Organization (WHO), and explains when to ask for help.
Feelings and thoughts
According to the NHS, psychological symptoms can include:
- a low mood or sadness that does not lift
- feeling hopeless or helpless
- low self-esteem and frequent tearfulness
- guilt
- irritability and impatience with others
- little motivation or interest in things
- difficulty making decisions
- little or no enjoyment of life
- anxiety or worry
- thoughts of harming yourself or ending your life
Changes in the body
The NHS says physical symptoms can include moving or speaking more slowly than usual, changes in appetite or weight, constipation, unexplained aches and pains, low energy, reduced sex drive and sleep problems such as trouble falling asleep or waking very early. MedlinePlus adds headaches and digestive problems to the list.
Changes in behaviour
Social symptoms described by the NHS include avoiding friends, taking part in fewer activities, neglecting hobbies and having difficulties at home, at work or in family life. MedlinePlus also mentions increased alcohol or drug use and withdrawing from family and friends.
Things worth knowing
- Few people have every symptom, according to the NHS.
- Depression often develops gradually, and many people do not realise they are unwell. A friend or family member may notice first.
- Doctors describe depression as mild, moderate or severe, depending on how often and how strongly symptoms occur, how long they last and how much they affect daily life.
- Some people with severe depression also have psychosis, which can include hallucinations or false beliefs.
- Teenagers may act out or seem unusually sleepy rather than look sad, according to MedlinePlus. Symptoms in older adults may be less obvious.
- Grief is a normal response to loss and usually eases over time. The NHS says suicidal thoughts, psychosis and constant hopelessness or guilt are less typical of grief.
How doctors recognise depression
MedlinePlus says diagnosis generally requires symptoms most of the day, nearly every day, for at least two weeks, including low mood or loss of interest. A health professional may take a medical history, do a physical exam and a mental health evaluation, and may run tests to rule out other causes such as thyroid problems or the effects of medicines. The WHO notes that depression can be mild, moderate or severe and can come back after a first episode.
When to see a doctor
The NHS advises seeing a doctor if you have symptoms of depression most of the day, every day, for more than two weeks. Low mood can improve after a short time, but if it does not, please do not wait. Early help can make symptoms easier to manage.
Go to a doctor sooner if:
- your low mood is making it hard to work, study or look after yourself
- you are using alcohol or drugs to cope
- you are worried about a friend or family member who seems to be struggling
If you are thinking about harming yourself
Thoughts of ending your life are a sign that you need support now, not a sign of weakness. Tell someone you trust, contact a doctor or counsellor, or call a crisis help line in your area. Help lines exist in both India and the United States, and a doctor or local health service can tell you which are available. Do not stay alone with these thoughts.
This article is for general education and is not a diagnosis.
In an emergency, call your local emergency number (112 in India, 911 in the United States).
Common questions
How long should low mood last before I see a doctor?
The NHS advises seeing a doctor if you have symptoms most of the day, every day, for more than two weeks.
Can depression cause physical symptoms?
Yes. The NHS lists slowed movement, appetite or weight changes, unexplained aches and pains, low energy and sleep problems among the physical symptoms.
Is grief the same as depression?
The NHS says grief usually improves over time, and suicidal thoughts, psychosis and constant hopelessness or guilt are less typical of grief.
Might someone else notice depression before I do?
Yes. The NHS says depression often develops gradually and a friend or family member may notice first.
Important: please read
- Educational information only. This article is general health education. It is not medical advice, diagnosis or treatment. Reading it does not create a doctor–patient relationship with MyDoctor or with anyone else.
- Ask a qualified doctor. Always talk to a qualified, registered doctor about your own health. In India, that means a doctor registered with the National Medical Commission (NMC) or a State Medical Council. In the United States, a licensed physician. Elsewhere, a doctor licensed where you live.
- Never ignore or delay professional advice because of something you read here. Do not start, stop or change any medicine or treatment without your doctor.
- Emergencies: call 112 in India, 911 in the United States, or your local emergency number. Do not wait for an online answer.
- If you are thinking about suicide or self-harm, or are in crisis: in India call Tele-MANAS on 14416 (free, 24 hours). In the United States call or text 988 (Suicide & Crisis Lifeline). Elsewhere, call your local emergency number.
- No product is endorsed. MyDoctor does not recommend any brand, product or supplement in this article.
- About the sources. This article summarises, in our own words, information from the public health bodies named under Sources. Health knowledge changes, and this summary may not reflect the latest research or your personal situation.
- Liability. To the extent permitted by law, MyDoctor (MODERNUS HEALTH TECHNOLOGIES PRIVATE LIMITED) accepts no liability for any decision made on the basis of this content.
Sources
- NHS. Clinical depression: Symptoms (NHS) www.nhs.uk
- NIH MedlinePlus. Depression (MedlinePlus) medlineplus.gov
- WHO. Depression fact sheet (WHO) www.who.int

Dr. Ambed Mishra, PharmD, PhD
- Clinical Research
- Psychiatry
- Community Medicine
- Clinical Pharmacy
- Electronic Health Records
- Patient Outcomes Research
MyDoctor by MODERN US HEALTH, Austin, Texas. Ahmedabad, Gujarat. Bangalore, India.
Dr. Ambed Mishra is a clinical (patient care) scientist, author and former professor. He is Group CEO and Chief Medical Officer of MODERN US HEALTH (MODERN US GROUP), Austin, Texas, the group behind MyDoctor, and a senior consultant who teaches and trains MD/DO physicians, PharmD and PhD professionals, nurses and other healthcare professionals in patient care in the United States and India.
More about Dr. Ambed Mishra
- More than ten years of full-time leadership in United States healthcare, building patient care services that improve medication adherence and bring doctors, pharmacists and nurses together around each patient.
- Leads the MD and engineering teams behind MyDoctor: clinic and hospital management software, electronic health records and telehealth for hospitals and physician groups in the United States and India.
- Former Assistant Professor and Clinical Preceptor at Rajiv Gandhi University of Health Sciences, Bangalore, and senior researcher with hospitals, universities and patient care groups in India and the United States.
- More than 30 published research and review articles and case reports, and more than 15 international conference presentations in India, Australia, Canada, the United States, Spain and other countries.
- Chief Medical Officer and Global Program Head of a nonprofit mission that helps cover hospital and doctor visit bills for patients in need in India, Nepal, the United States and other countries.
The author's office answers questions about articles, research, speaking and collaboration. It cannot give personal medical advice.