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Mental health

Depression Treatment: Therapy, Medicines and Self-Help Explained

Depression is treatable. This article describes the main approaches, from self-help and talking therapy to prescribed medicines, as explained by the NHS, WHO and MedlinePlus.

3 min readUpdated 3 official sources

Dr. Ambed MishraScientist and Chief Medical OfficerDr. Ambed Mishra

Educational information only, not medical advice. Always ask a qualified doctor about your own health. In an emergency call 112 (India) or 911 (US). For mental health support call Tele-MANAS 14416 (India) or 988 (US). Read the full disclaimer.

On this page
  1. Mild depression
  2. Talking therapies
  3. Medicines
  4. Other treatments for severe depression
  5. Everyday habits
  6. When to see a doctor
  7. Common questions
  8. Sources
  9. About the author

Depression can feel overwhelming, but it is a condition with recognised treatments. The right approach depends on how severe the depression is and on the person, so a doctor or mental health professional should guide the choice. This article describes what the NHS, WHO and MedlinePlus say in general terms.

Mild depression

For mild depression, the NHS says a doctor may first suggest "watchful waiting", which means a review after 2 to 4 weeks. Other options include:

  • Guided self-help: usually 6 to 8 sessions working through a workbook or online course with support from a therapist, based on cognitive behavioural therapy (CBT) ideas.
  • Exercise: the NHS describes it as one of the main treatments for mild depression, and group exercise classes may be offered.
  • Group mindfulness: recommended as an option for less severe depression.

The NHS also says that St John's wort is not recommended by doctors. Products vary in what they contain, and it can interact with other medicines. Please speak to a doctor before using any herbal product.

Talking therapies

Talking therapies help people understand and change patterns in thoughts, feelings and behaviour. The NHS lists several, usually delivered over about 8 to 16 sessions:

  • CBT, which looks at present thoughts and behaviour
  • interpersonal therapy, which focuses on relationships
  • behavioural activation, which links activities to mood
  • counselling, which helps with coping
  • psychodynamic psychotherapy, which explores patterns in feelings and relationships

The WHO also names behavioural activation, CBT, interpersonal psychotherapy and problem-solving therapy as effective psychological treatments, and says that psychological treatment is a first-line option.

Medicines

Antidepressants are prescribed by a doctor, usually for moderate or severe depression. According to the NHS, most people with moderate or severe depression benefit, but not everyone does, and more than one medicine may need to be tried. The WHO says antidepressants are not needed for mild depression. For moderate and severe depression, psychological treatment can be combined with medicines, and the NHS says the combination usually works better than either alone.

Medicines come in different classes with different side effects, and a doctor chooses based on the person. The NHS and WHO both say extra caution is needed with children and teenagers.

Some points to remember:

  • The NHS says symptoms should start to improve within about 4 weeks of starting an antidepressant, and doctors review progress regularly in the early weeks.
  • Contact a doctor straight away if hopelessness or thoughts of suicide start or get worse after starting a medicine.
  • Do not stop a medicine suddenly. The NHS says doses should be reduced gradually to avoid withdrawal symptoms.

Other treatments for severe depression

MedlinePlus says that when depression is severe or other treatments have not worked, specialists may consider brain stimulation methods. These are only arranged by a specialist team after assessment.

Everyday habits

MedlinePlus says most depression cannot be prevented, but regular exercise, a consistent sleep schedule and managing stress support long-term mental health.

When to see a doctor

Please see a doctor if you think you may be depressed, if you have felt low most of the day, every day for two weeks or more, or if you are already in treatment and it does not seem to be helping. If you have thoughts of harming yourself, contact a doctor, counsellor or crisis help line in your area immediately. Help lines exist in India and the United States and a local health service can tell you which are available.

Do not stop or change prescribed treatment without talking to your doctor.

In an emergency, call your local emergency number (112 in India, 911 in the United States).

Common questions

Do I always need medicine for depression?

No. The WHO says antidepressants are not needed for mild depression. A doctor decides what is right for each person.

How long does therapy for depression usually take?

The NHS says many talking therapies are usually delivered over about 8 to 16 sessions, though this varies by type.

Is exercise a treatment for depression?

The NHS describes exercise as one of the main treatments for mild depression, alongside other options chosen with a doctor.

Can I stop an antidepressant when I feel better?

Not without medical advice. The NHS says doses should be reduced gradually to avoid withdrawal symptoms.

Important: please read

  • Educational information only. This article is general health education. It is not medical advice, diagnosis or treatment. Reading it does not create a doctor–patient relationship with MyDoctor or with anyone else.
  • Ask a qualified doctor. Always talk to a qualified, registered doctor about your own health. In India, that means a doctor registered with the National Medical Commission (NMC) or a State Medical Council. In the United States, a licensed physician. Elsewhere, a doctor licensed where you live.
  • Never ignore or delay professional advice because of something you read here. Do not start, stop or change any medicine or treatment without your doctor.
  • Emergencies: call 112 in India, 911 in the United States, or your local emergency number. Do not wait for an online answer.
  • If you are thinking about suicide or self-harm, or are in crisis: in India call Tele-MANAS on 14416 (free, 24 hours). In the United States call or text 988 (Suicide & Crisis Lifeline). Elsewhere, call your local emergency number.
  • No product is endorsed. MyDoctor does not recommend any brand, product or supplement in this article.
  • About the sources. This article summarises, in our own words, information from the public health bodies named under Sources. Health knowledge changes, and this summary may not reflect the latest research or your personal situation.
  • Liability. To the extent permitted by law, MyDoctor (MODERNUS HEALTH TECHNOLOGIES PRIVATE LIMITED) accepts no liability for any decision made on the basis of this content.

Full disclaimer · Privacy and terms

Sources

  1. NHS. Clinical depression: Treatment (NHS) www.nhs.uk
  2. WHO. Depression fact sheet (WHO) www.who.int
  3. NIH MedlinePlus. Depression (MedlinePlus) medlineplus.gov
Dr. Ambed Mishra
Scientist and Chief Medical Officer

Dr. Ambed Mishra, PharmD, PhD

  • Clinical Research
  • Psychiatry
  • Community Medicine
  • Clinical Pharmacy
  • Electronic Health Records
  • Patient Outcomes Research
MyDoctormydoctor.social

MyDoctor by MODERN US HEALTH, Austin, Texas. Ahmedabad, Gujarat. Bangalore, India.

Dr. Ambed Mishra is a clinical (patient care) scientist, author and former professor. He is Group CEO and Chief Medical Officer of MODERN US HEALTH (MODERN US GROUP), Austin, Texas, the group behind MyDoctor, and a senior consultant who teaches and trains MD/DO physicians, PharmD and PhD professionals, nurses and other healthcare professionals in patient care in the United States and India.

More about Dr. Ambed Mishra
  • More than ten years of full-time leadership in United States healthcare, building patient care services that improve medication adherence and bring doctors, pharmacists and nurses together around each patient.
  • Leads the MD and engineering teams behind MyDoctor: clinic and hospital management software, electronic health records and telehealth for hospitals and physician groups in the United States and India.
  • Former Assistant Professor and Clinical Preceptor at Rajiv Gandhi University of Health Sciences, Bangalore, and senior researcher with hospitals, universities and patient care groups in India and the United States.
  • More than 30 published research and review articles and case reports, and more than 15 international conference presentations in India, Australia, Canada, the United States, Spain and other countries.
  • Chief Medical Officer and Global Program Head of a nonprofit mission that helps cover hospital and doctor visit bills for patients in need in India, Nepal, the United States and other countries.

The author's office answers questions about articles, research, speaking and collaboration. It cannot give personal medical advice.

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