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Diabetes and thyroid

High blood sugar (hyperglycemia): causes, signs and what to do

High blood sugar, or hyperglycemia, mostly affects people with diabetes. This review explains the signs, common causes, what to check, how to lower the risk and when to call a doctor or go to hospital.

5 min readUpdated 3 official sources

Dr. Ambed MishraScientist and Chief Medical OfficerDr. Ambed Mishra

Educational information only, not medical advice. Always ask a qualified doctor about your own health. In an emergency call 112 (India) or 911 (US). Read the full disclaimer.

Simple view: the same facts in everyday words, for readers with no medical background.

Abstract

Background. High blood sugar, also called hyperglycemia, happens when there is too much glucose in the blood. It mostly affects people with diabetes, because the body makes too little insulin or cannot use it properly.

Key points. This review describes the usual signs, such as thirst, passing urine often, tiredness and blurred vision, which can build up slowly. It lists common triggers, including illness, stress, missed medicine, extra sugary or starchy food and less activity. It explains what a person can check at home, the longer term risks of repeated high levels and the warning signs that need urgent care.

Conclusion. Short, mild rises are usually not serious, but readings that stay high need a call to your care team. Seek emergency help for vomiting, drowsiness, confusion, fast breathing or fruity-smelling breath. Medicine changes are always decided by your doctor.

Keywords: high blood sugar; hyperglycemia symptoms; high blood glucose; blood sugar too high; diabetes high sugar causes; what to do high blood sugar

On this page
  1. 1. Introduction
  2. 2. Signs and symptoms
  3. 3. Causes and triggers
  4. 4. Blood sugar numbers
  5. 5. Why repeated high levels matter
  6. 6. Lowering the risk
  7. 7. When to see a doctor
  8. 8. Conclusion
  9. Common questions
  10. References
  11. Article information
  12. Cite this article
  13. About the author

High blood sugar mainly affects people living with diabetes. This article explains what it is, why it happens, what you can check yourself and when to get help. It draws on MedlinePlus and the NHS.

1. Introduction

High blood sugar is also called high blood glucose or hyperglycemia (the medical word). Glucose is the sugar that gives the body energy. MedlinePlus explains that insulin, a hormone, normally moves glucose out of the blood and into muscle and fat cells [1]. When the body makes too little insulin, or the cells do not respond to it well, glucose stays in the blood and levels rise [1].

The NHS says high blood sugar mainly affects people with diabetes and can become serious if it is not dealt with [2]. The NHS also describes diabetes as a condition in which the body makes too little insulin, none at all, or cannot use it properly, which is called insulin resistance [3].

2. Signs and symptoms

The NHS notes that symptoms often develop slowly and may only show up when blood sugar is very high [2]. Common signs listed by the NHS and MedlinePlus include [1, 2]:

  • Feeling very thirsty or having a dry mouth
  • Passing urine a lot
  • Feeling weak or tired
  • Blurred vision
  • Dry skin
  • Weight loss

MedlinePlus adds that very high or long-lasting high blood sugar can weaken the immune system, which raises the chance of infections [1]. Because symptoms can be easy to miss, checking blood sugar as your care team advises is the only sure way to know your level.

3. Causes and triggers

In people with diabetes, the NHS lists several common triggers [2]:

  • Being unwell
  • Stress
  • Eating too much sugary or starchy food
  • Being less active than usual
  • Missing diabetes medicine

The NHS also mentions diabetes medicine that is not working well, some other medicines such as steroids, and recent surgery [2]. MedlinePlus agrees that stress from surgery, infection or trauma can push blood sugar up for a while, and that it usually settles once the stress passes [1].

What to check when readings are high

MedlinePlus suggests thinking through a short checklist [1]:

  • Food: have you eaten more than planned, or more carbohydrate (starch and sugar) than usual?
  • Medicines: has your doctor changed them, and are you taking them as directed? If you use insulin, check it has not expired and has been stored correctly.
  • Injection sites: injecting into a scar, a lump or a numb area can affect how insulin works, so rotate the sites.
  • Other changes: less activity, illness with fever, dehydration, stress, weight gain or not checking your blood sugar regularly.

4. Blood sugar numbers

The NHS gives a guide, and says levels can differ by age and type of diabetes [2]. In general, a home reading above 7 mmol/L on waking or before eating, or above 11 mmol/L at least 90 minutes after eating, is described as high. Your own targets are set with your care team, so use their numbers first.

A blood test called HbA1c shows average blood sugar over about two to three months. The NHS lists 48 mmol/mol (6.5%) or over as a high level [2].

5. Why repeated high levels matter

The NHS says occasional, slight and short-lived highs are usually not serious. Long periods of high blood sugar can damage nerves in the hands and feet, harm the eyes (diabetic retinopathy) and raise the risk of heart disease and stroke [2]. A very serious problem called diabetic ketoacidosis can also develop [2]. Ketones are acids the body makes when it breaks down fat for energy because it lacks insulin. The NHS says your care team may ask you to test your blood or urine for ketones, and a high level is a sign of ketoacidosis [2].

MedlinePlus gives a general guide for testing urine ketones when high readings have no clear reason: after about 3 days above goal in type 2 diabetes, or about 6 hours above goal in type 1 diabetes. If ketones are present, it advises contacting your provider or getting emergency care [1]. Ask your own doctor which rule applies to you.

6. Lowering the risk

Steps named by MedlinePlus and the NHS include [1, 2]:

  • Take your diabetes medicines as your doctor directs, and do not skip or change them unless your care team tells you to.
  • Follow your meal plan and avoid eating too much sugary or starchy food.
  • Stay physically active.
  • Manage stress.
  • Aim for a healthy weight.
  • Agree target blood sugar levels, and how often to check, with your provider.
  • Follow your "sick day rules" when you are unwell.

7. When to see a doctor

Contact your care team or GP surgery if your blood sugar stays high, or symptoms continue after you have tried the steps above [2]. MedlinePlus says to call your provider when readings are too high or too low and you do not understand why [1]. The NHS also advises seeing a doctor if you have symptoms of high blood sugar but have not been told you have diabetes [2].

Seek urgent help if high blood sugar comes with any of these, according to the NHS [2]:

  • Feeling sick, being sick or stomach pain
  • Breathing faster, or a faster heartbeat than usual
  • Feeling drowsy or finding it hard to stay awake
  • Breath that smells fruity
  • Confusion or difficulty concentrating
  • High ketone levels in blood or urine

The NHS advises not to drive yourself to hospital: ask someone to take you or call an ambulance, and bring your medicines [2]. In an emergency, call your local emergency number (112 in India, 911 in the United States).

8. Conclusion

High blood sugar is common in diabetes and often has an identifiable trigger, such as illness, stress, missed medicine or a change in food or activity. Short, mild rises are usually not dangerous, but readings that stay high, or high readings with vomiting, drowsiness, confusion or fast breathing, need medical attention. Your doctor decides any change to your treatment.

Common questions

What is a high blood sugar reading?

The NHS gives a guide of above 7 mmol/L on waking or before eating, or above 11 mmol/L at least 90 minutes after a meal. Your care team may set different targets for you.

Can being ill raise my blood sugar?

Yes. Both the NHS and MedlinePlus list illness and stress as common triggers. Ask your care team for a sick day plan.

Does high blood sugar always cause symptoms?

No. The NHS says symptoms often build up slowly and may only appear when levels are very high, so regular checks matter.

When is high blood sugar an emergency?

The NHS says to seek urgent help if it comes with vomiting, stomach pain, fast breathing, drowsiness, confusion, fruity-smelling breath or high ketones.

Important: please read

  • Educational information only. This article is general health education. It is not medical advice, diagnosis or treatment. Reading it does not create a doctor–patient relationship with MyDoctor or with anyone else.
  • Ask a qualified doctor. Always talk to a qualified, registered doctor about your own health. In India, that means a doctor registered with the National Medical Commission (NMC) or a State Medical Council. In the United States, a licensed physician. Elsewhere, a doctor licensed where you live.
  • Never ignore or delay professional advice because of something you read here. Do not start, stop or change any medicine or treatment without your doctor.
  • Emergencies: call 112 in India, 911 in the United States, or your local emergency number. Do not wait for an online answer.
  • No product is endorsed. MyDoctor does not recommend any brand, product or supplement in this article.
  • About the sources. This article summarises, in our own words, information from the public health bodies named under Sources. Health knowledge changes, and this summary may not reflect the latest research or your personal situation.
  • Liability. To the extent permitted by law, MyDoctor (MODERNUS HEALTH TECHNOLOGIES PRIVATE LIMITED) accepts no liability for any decision made on the basis of this content.

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References

  1. NIH MedlinePlus. High blood sugar - self-care [Internet]. 2026 [cited 2026 Oct 19]. Available from: https://medlineplus.gov/ency/patientinstructions/000332.htm
  2. NHS. High blood sugar (hyperglycaemia) [Internet]. 2025 [cited 2026 Oct 19]. Available from: https://www.nhs.uk/conditions/high-blood-sugar-hyperglycaemia/
  3. NHS. Diabetes [Internet]. 2025 [cited 2026 Oct 19]. Available from: https://www.nhs.uk/conditions/diabetes/

Article information

Article ID
MDG-ART-DIABETES-0001
Version
1
Author and corresponding author
Dr. Ambed Mishra, PharmD, PhD, Scientist and Chief Medical Officer, MyDoctor. Contact the author's office
Written
2026 Oct 10
Approved and published
2026 Oct 20
Last reviewed
2026 Oct 20
Next review due
2027 Oct 20
Conflict of interest
The author leads MyDoctor, which offers health services. No company paid for this article.
Funding
None.

Cite this article

NLM (PubMed style)

Mishra A. High blood sugar (hyperglycemia): causes, signs and what to do [Internet]. MyDoctor Health Library. 2026 [updated 2026 Oct 20; cited 2026 Oct 20]. Available from: https://mydoctor.social/app/blog/high-blood-sugar-hyperglycemia-causes-and-what-to-do

AMA

Mishra A. High blood sugar (hyperglycemia): causes, signs and what to do. MyDoctor Health Library. Published October 20, 2026. Updated October 20, 2026. Accessed October 20, 2026. https://mydoctor.social/app/blog/high-blood-sugar-hyperglycemia-causes-and-what-to-do

APA

Mishra, A. (2026, October 20). High blood sugar (hyperglycemia): causes, signs and what to do. MyDoctor Health Library. https://mydoctor.social/app/blog/high-blood-sugar-hyperglycemia-causes-and-what-to-do

Dr. Ambed Mishra
Scientist and Chief Medical Officer

Dr. Ambed Mishra, PharmD, PhD

  • Clinical Research
  • Psychiatry
  • Community Medicine
  • Clinical Pharmacy
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MyDoctormydoctor.social

MyDoctor by MODERN US HEALTH, Austin, Texas. Ahmedabad, Gujarat. Bangalore, India.

Dr. Ambed Mishra is a clinical (patient care) scientist, author and former professor. He is Group CEO and Chief Medical Officer of MODERN US HEALTH (MODERN US GROUP), Austin, Texas, the group behind MyDoctor, and a senior consultant who teaches and trains MD/DO physicians, PharmD and PhD professionals, nurses and other healthcare professionals in patient care in the United States and India.

More about Dr. Ambed Mishra
  • More than ten years of full-time leadership in United States healthcare, building patient care services that improve medication adherence and bring doctors, pharmacists and nurses together around each patient.
  • Leads the MD and engineering teams behind MyDoctor: clinic and hospital management software, electronic health records and telehealth for hospitals and physician groups in the United States and India.
  • Former Assistant Professor and Clinical Preceptor at Rajiv Gandhi University of Health Sciences, Bangalore, and senior researcher with hospitals, universities and patient care groups in India and the United States.
  • More than 30 published research and review articles and case reports, and more than 15 international conference presentations in India, Australia, Canada, the United States, Spain and other countries.
  • Chief Medical Officer and Global Program Head of a nonprofit mission that helps cover hospital and doctor visit bills for patients in need in India, Nepal, the United States and other countries.

The author's office answers questions about articles, research, speaking and collaboration. It cannot give personal medical advice.

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