What Is Depression? Causes, Types and Where to Find Help
Depression is a common but serious mood condition that affects feelings, thinking and daily life. This article explains what it is, what contributes to it and how help is available.
Educational information only, not medical advice. Always ask a qualified doctor about your own health. In an emergency call 112 (India) or 911 (US). For mental health support call Tele-MANAS 14416 (India) or 988 (US). Read the full disclaimer.
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Many people say they feel "depressed" after a bad week. Clinical depression is different. It is a recognised health condition that can be treated, and it is nothing to be ashamed of. This article gives a plain-English overview.
What is depression?
According to the World Health Organization (WHO), depression is a common mental disorder in which a person has a low mood or loses pleasure or interest in things for long periods. It can affect relationships, school and work. The US National Institute of Mental Health (NIMH) says it can affect anyone, whatever their age, race, income, culture or education, and that ordinary sadness usually passes with time while depression does not.
MedlinePlus describes depression as more than feeling sad or irritable for a few days. It can change how a person thinks and feels, and affect sleep, eating and work.
Types of depression
MedlinePlus lists several forms:
- Major depression: low mood or loss of interest that disrupts daily life and lasts at least two weeks.
- Persistent depressive disorder: milder symptoms that last at least two years.
- Seasonal affective disorder: depression that returns with the seasons, usually starting in late autumn or early winter.
- Bipolar disorder: intense mood swings, formerly called manic depression.
- Depression with psychosis: a severe form that includes false beliefs or hallucinations.
The WHO also describes depressive episodes as mild, moderate or severe, and notes that depression can be a single episode or can come back.
What causes depression?
There is usually no single cause. The WHO says depression results from a mix of social, psychological and biological factors. Difficult life events such as unemployment, bereavement and trauma raise the risk. NIMH adds that genetic, biological, environmental and psychological factors all play a part. MedlinePlus notes that having a close relative with depression raises risk, and that in some people no clear cause is found.
Depression and physical illness are linked too. The WHO says depression is closely connected with conditions such as heart disease, cancer, diabetes and lung disease, and MedlinePlus says long-term conditions and depression can make each other worse.
How common is it?
According to the WHO, around 4% of the world's population had depression in 2023. Among adults the figure was 5.2%, and it was about 1.5 times more common in women than in men. The WHO also reports that in high-income countries only about one third of people with depression receive mental health treatment.
Can depression be treated?
Yes. The WHO says effective treatments exist, including psychological treatments and medicines, and that talking therapies are usually the first option. For moderate or severe depression, a doctor may suggest combining the two. MedlinePlus also mentions other approaches for severe cases that have not responded to other treatment, which only a specialist can arrange. A doctor decides what suits each person, and nobody should start or stop a medicine without medical advice.
Why stigma matters
The WHO points out that social stigma around mental health conditions is a barrier to getting care. Depression is a health condition, not a weakness or a character flaw. Talking to someone you trust and then to a doctor is a good first step.
When to see a doctor
See a doctor if low mood, loss of interest or hopelessness lasts most of the day, nearly every day, for two weeks or more, or if it is getting in the way of work, study, family life or relationships. Early help can make symptoms easier to manage, according to MedlinePlus.
If you have thoughts of harming yourself or ending your life, please reach out right now. You are not alone and many people have found help. Tell a trusted person, contact a doctor or counsellor, or call a crisis help line in your area. Help lines exist in both India and the United States, and a doctor or local health service can tell you which are available near you.
This article is for general education and is not a diagnosis. Do not stop or change prescribed treatment without talking to your doctor.
In an emergency, call your local emergency number (112 in India, 911 in the United States).
Common questions
Is depression the same as sadness?
No. NIMH says ordinary sadness usually passes with time, while depression does not and can affect daily life.
How long do symptoms need to last for depression to be diagnosed?
MedlinePlus says diagnosis generally requires symptoms most of the day, nearly every day, for at least two weeks.
Is depression common?
According to the WHO, an estimated 4% of the world's population had depression in 2023.
Can depression be treated?
The WHO says effective treatments exist, including psychological treatment and medicines. A doctor decides which is right for each person.
Important: please read
- Educational information only. This article is general health education. It is not medical advice, diagnosis or treatment. Reading it does not create a doctor–patient relationship with MyDoctor or with anyone else.
- Ask a qualified doctor. Always talk to a qualified, registered doctor about your own health. In India, that means a doctor registered with the National Medical Commission (NMC) or a State Medical Council. In the United States, a licensed physician. Elsewhere, a doctor licensed where you live.
- Never ignore or delay professional advice because of something you read here. Do not start, stop or change any medicine or treatment without your doctor.
- Emergencies: call 112 in India, 911 in the United States, or your local emergency number. Do not wait for an online answer.
- If you are thinking about suicide or self-harm, or are in crisis: in India call Tele-MANAS on 14416 (free, 24 hours). In the United States call or text 988 (Suicide & Crisis Lifeline). Elsewhere, call your local emergency number.
- No product is endorsed. MyDoctor does not recommend any brand, product or supplement in this article.
- About the sources. This article summarises, in our own words, information from the public health bodies named under Sources. Health knowledge changes, and this summary may not reflect the latest research or your personal situation.
- Liability. To the extent permitted by law, MyDoctor (MODERNUS HEALTH TECHNOLOGIES PRIVATE LIMITED) accepts no liability for any decision made on the basis of this content.
Sources
- WHO. Depression fact sheet (WHO) www.who.int
- NIH MedlinePlus. Depression (MedlinePlus) medlineplus.gov
- NIMH. Depression (NIMH) www.nimh.nih.gov

Dr. Ambed Mishra, PharmD, PhD
- Clinical Research
- Psychiatry
- Community Medicine
- Clinical Pharmacy
- Electronic Health Records
- Patient Outcomes Research
MyDoctor by MODERN US HEALTH, Austin, Texas. Ahmedabad, Gujarat. Bangalore, India.
Dr. Ambed Mishra is a clinical (patient care) scientist, author and former professor. He is Group CEO and Chief Medical Officer of MODERN US HEALTH (MODERN US GROUP), Austin, Texas, the group behind MyDoctor, and a senior consultant who teaches and trains MD/DO physicians, PharmD and PhD professionals, nurses and other healthcare professionals in patient care in the United States and India.
More about Dr. Ambed Mishra
- More than ten years of full-time leadership in United States healthcare, building patient care services that improve medication adherence and bring doctors, pharmacists and nurses together around each patient.
- Leads the MD and engineering teams behind MyDoctor: clinic and hospital management software, electronic health records and telehealth for hospitals and physician groups in the United States and India.
- Former Assistant Professor and Clinical Preceptor at Rajiv Gandhi University of Health Sciences, Bangalore, and senior researcher with hospitals, universities and patient care groups in India and the United States.
- More than 30 published research and review articles and case reports, and more than 15 international conference presentations in India, Australia, Canada, the United States, Spain and other countries.
- Chief Medical Officer and Global Program Head of a nonprofit mission that helps cover hospital and doctor visit bills for patients in need in India, Nepal, the United States and other countries.
The author's office answers questions about articles, research, speaking and collaboration. It cannot give personal medical advice.